Abstract: gelastic seizures are focal epileptic seizures that involve sudden outbursts of forced laughter.In our study Gelastic seizures were revealed in 25 patients that comprised 1,98% of all epilepsy events with onset under 18 years of age (n=1261).Male patients prevailed in the group: 16 male patients SHINE (64.
0%) against 9 female patients (36.0%).Symptomatic focal epilepsy was identified most frequently - in 80% of patients.
Cryptogenic focal epilepsy (probably symptomatic focal epilepsy) was defined in 20% of cases.Epilepsy onset varied in a broad age interval: from the first day after birth till 16 years, 4.53+4.
52 years on average.Most often (82%) onset was observed in the first years of life - from the first days of life till 6 years old.Clinical findings may disclose 12 different types of seizures.
Most frequently were observed: focal motor seizures with typical automatisms - 64% of cases, secondarily generalized tonic-clonic seizures - 48% of cases and tonic seizures - in 32% of all cases.MRI changes: hypothalamic hamartoma - 32% of cases, temporal lobe atrophy - 12% of cases, DNET - 8% of cases, focal cortical dysplasia (insular-opercular region) - 4%, local bifrontal atrophy - 8%, Tuberous B1 Vitamins / Thiamine Sclerosis - 8% of cases, diffuse cerebral atrophy presented in the form of ventriculomegalia was diagnosed in 2 patients - 8% of cases.Remission was achieved only in 24% of cases.
Whereas, in 12% of cases seizures were blocked only after surgical intervention.Reduction of seizures frequency >50% was observed in 20% of patients.In 56% of cases AED therapy produced no significant effect.